November 24, 2025

Vita Nectar

Health is the main investment in life

Expert consensus on the treatment of oral diseases in pregnant women and infants

Expert consensus on the treatment of oral diseases in pregnant women and infants
  • Xiao, J. et al. Prenatal oral health care and early childhood caries prevention: A systematic review and meta-analysis. Caries Res. 53, 411–421 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Lee, H. et al. Oral health is an integral part of maternal and child health. J. Public Health Policy 45, 595–601 (2024).

    Article 
    PubMed 

    Google Scholar 

  • Iida, H. Oral health interventions during pregnancy. Dent. Clin. North Am. 61, 467–481 (2017).

    Article 
    PubMed 

    Google Scholar 

  • Daalderop, L. A. et al. Periodontal disease and pregnancy outcomes: Overview of systematic reviews. JDR Clin. Trans. Res. 3, 10–27 (2018).

    CAS 
    PubMed 

    Google Scholar 

  • Chaffee, B. W. et al. Maternal oral bacterial levels predict early childhood caries development. J. Dent. Res. 93, 238–244 (2014).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bao, J. et al. Clinical practice guidelines for oral health care during pregnancy: a systematic evaluation and summary recommendations for general dental practitioners. Quintessence Int. 53, 362–373 (2022).

    PubMed 

    Google Scholar 

  • Radwan-Oczko, M. et al. How much do pregnant women know about the importance of oral health in pregnancy? Questionnaire-based survey. BMC Pregnancy Childbirth 23, 348 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Dolic, O. et al. Caries increment in Bosnian women associated with caries risk factors according to the Cariogram during pregnancy: A four-year longitudinal study. Eur. J. Paediatr. Dent. 23, 69–72 (2022).

    CAS 
    PubMed 

    Google Scholar 

  • Wu, Y. et al. Association between pica practice, oral health, and cariogenic microorganisms of US pregnant women: A cross-sectional study. Arch. Oral. Biol. 175, 106277 (2025).

    Article 
    PubMed 

    Google Scholar 

  • Alnakhli, Z. H. et al. Dental caries, gingivitis, and oral health in pregnant women: An updated review article. Rev. Contemp. Philos. 22, 623–640 (2023).

    Google Scholar 

  • Deghatipour, M. et al. Effect of oral health promotion interventions on pregnant women dental caries: a field trial. BMC Oral. Health 22, 280 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rakchanok, N. et al. Dental caries and gingivitis among pregnant and non-pregnant women in Chiang Mai, Thailand. Nagoya J. Med. Sci. 72, 43–50 (2010).

    PubMed 
    PubMed Central 

    Google Scholar 

  • Rocha, J. S. et al. Determinants of dental care attendance during pregnancy: A systematic review. Caries Res. 52, 139–152 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Tenenbaum, A. & Azogui-Levy, S. Oral health knowledge, attitudes, practices, and literacy of pregnant women: A scoping review. Oral. Health Prev. Dent. 21, 185–198 (2023).

    PubMed 

    Google Scholar 

  • Goettems, M. L. et al. Children’s use of dental services: influence of maternal dental anxiety, attendance pattern, and perception of children’s quality of life. Community Dent. Oral. Epidemiol. 40, 451–458 (2012).

    Article 
    PubMed 

    Google Scholar 

  • Olak, J. et al. The influence of mothers’ oral health behaviour and perception thereof on the dental health of their children. EPMA J. 9, 187–193 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Jahan, S. S. et al. Oral healthcare during pregnancy: its importance and challenges in lower-middle-income countries (LMICs). Int. J. Environ. Res. Public Health 19, 10681 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Lee, H. Introducing maternal oral health as global health and public health agenda. Eur. J. Public Health 32, ckac129.257 (2022).

    Article 
    PubMed Central 

    Google Scholar 

  • Beauchemin, M. et al. Implementation of clinical practice guidelines in the health care setting: A concept analysis. ANS Adv. Nurs. Sci. 42, 307–324 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Nanci, A. Ten Cate’s Oral Histology, Edition 10: Development, Structure, and Function (Elsevier Health Sciences, 2024).

  • Sadeghianrizi, A. et al. Craniofacial development in obese adolescents. Eur. J. Orthod. 27, 550–555 (2005).

    Article 
    PubMed 

    Google Scholar 

  • Pirinen, S. Endocrine regulation of craniofacial growth. Acta Odontol. Scand. 53, 179–185 (1995).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Pelin, C. et al. Body height estimation from head and face dimensions: a different method. J. Forensic Sci. 55, 1326–1330 (2010).

    Article 
    PubMed 

    Google Scholar 

  • Shrestha, R. et al. Craniometric analysis for estimation of stature in Nepalese population—A study on an autopsy sample. Forensic Sci. Int. 248, 187.e1–187.e6 (2015).

    Article 
    PubMed 

    Google Scholar 

  • Flores-Mir, C. et al. Use of skeletal maturation based on hand-wrist radiographic analysis as a predictor of facial growth: a systematic review. Angle Orthod. 74, 118–124 (2004).

    PubMed 

    Google Scholar 

  • Helm, S. et al. Skeletal maturation of the hand in relation to maximum puberal growth in body height. Tandlaegebladet 75, 1223–1234 (1971).

    CAS 
    PubMed 

    Google Scholar 

  • Mellion, Z. J. et al. The pattern of facial skeletal growth and its relationship to various common indexes of maturation. Am. J. Orthod. Dentofac. Orthop. 143, 845–854 (2013).

    Article 

    Google Scholar 

  • Verma, D. et al. Reliability of growth prediction with hand-wrist radiographs. Eur. J. Orthod. 31, 438–442 (2009).

    Article 
    PubMed 

    Google Scholar 

  • Vucic, S. et al. Dental development and craniofacial morphology in school-age children. Am. J. Orthod. Dentofac. Orthop. 156, 229–237.e4 (2019).

    Article 

    Google Scholar 

  • Wilkes, C. et al. Prenatal diagnosis of cleft lip and/or palate: What do we tell prospective parents?. Prenat. Diagn. 43, 1310–1319 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Sadler, T. W.(ed.) Langman’s Medical Embryology 15th edn (Wolters Kluwer, 2023)

  • Ooë, T. (eds) Human Tooth and Dental Arch Development (Ishiyaku Publishers, 1981).

  • Yu, T. et al. Stem cells in tooth development, growth, repair, and regeneration. Curr. Top. Dev. Biol. 115, 187–212 (2015).

    Article 
    PubMed 

    Google Scholar 

  • González-Fernández, D. et al. Associations of maternal nutritional status and supplementation with fetal, newborn, and infant outcomes in low-income and middle-income settings: An overview of reviews. Nutrients 16, 3725 (2024).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Morrison, J. L. & Regnault, T. R. Nutrition in pregnancy: Optimising maternal diet and fetal adaptations to altered nutrient supply. Nutrients 8, 342 (2016).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gómez-Roig, M. D. et al. Environmental exposure during pregnancy: Influence on prenatal development and early life: A comprehensive review. Fetal Diagn. Ther. 48, 245–257 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Bislev, L. S. et al. Vitamin D and muscle health: A systematic review and meta-analysis of randomized placebo-controlled trials. J. Bone Miner. Res. 36, 1651–1660 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Via, W. F. Jr & Churchill, J. A. Relationship of enamel hypoplasia to abnormal events of gestation and birth. J. Am. Dent. Assoc. 59, 702–707 (1959).

    Article 
    PubMed 

    Google Scholar 

  • Norén, J. G. Microscopic study of enamel defects in deciduous teeth of infants of diabetic mothers. Acta Odontol. Scand. 42, 153–156 (1984).

    Article 
    PubMed 

    Google Scholar 

  • Ye, W. et al. Association between maternal diabetes and neurodevelopmental outcomes in children: a systematic review and meta-analysis of 202 observational studies comprising 56·1 million pregnancies. Lancet Diab. Endocrinol. 13, 494–504 (2025).

    Article 

    Google Scholar 

  • Corrêa-Faria, P. et al. Developmental defects of enamel in primary teeth: prevalence and associated factors. Int. J. Paediatr. Dent. 23, 173–179 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Aagaard, K. et al. The placenta harbors a unique microbiome. Sci. Transl. Med. 6, 237ra65 (2014).

    PubMed 
    PubMed Central 

    Google Scholar 

  • Finlayson, T. L. et al. Prenatal maternal factors, intergenerational transmission of disease, and child oral health outcomes. Dent. Clin. North Am. 61, 483–518 (2017).

    Article 
    PubMed 

    Google Scholar 

  • Yang, E. Y. et al. Periodontal pathogen detection in gingiva/tooth and tongue flora samples from 18- to 48-month-old children and periodontal status of their mothers. Oral. Microbiol. Immunol. 17, 55–59 (2002).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Yatsunenko, T. et al. Human gut microbiome viewed across age and geography. Nature 486, 222–227 (2012).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ferretti, P. et al. Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome. Cell Host Microbe 24, 133–145.e5 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Argaw-Denboba, A. et al. Paternal microbiome perturbations impact offspring fitness. Nature 629, 652–659 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kaan, A. M. M. et al. Acquisition and establishment of the oral microbiota. Periodontol 2000 86, 123–141 (2021).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Boustedt, K. et al. Salivary microflora and mode of delivery: a prospective case control study. BMC Oral. Health 15, 155 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zimmermann, P. & Curtis, N. Factors Influencing the Intestinal Microbiome During the First Year of Life. Pediatr. Infect. Dis. J. 37, e315–e335 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Smaill, F. M. & Grivell, R. M. Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. Cochrane Database Syst. Rev. 10, CD007482 (2014).

    Google Scholar 

  • Gomez-Arango, L. F. et al. Antibiotic treatment at delivery shapes the initial oral microbiome in neonates. Sci. Rep. 7, 43481 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Cabrera-Rubio, R. et al. The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery. Am. J. Clin. Nutr. 96, 544–551 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Toscano, M. et al. Impact of delivery mode on the colostrum microbiota composition. BMC Microbiol 17, 205 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Costello, E. K. et al. Microbiome assembly across multiple body sites in low-birthweight infants. mBio 4, e00782–13 (2013).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chu, D. M. et al. Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery. Nat. Med. 23, 314–326 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Drell, T. et al. The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota. Sci. Rep. 7, 9940 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rodríguez, J. M. The origin of human milk bacteria: is there a bacterial entero-mammary pathway during late pregnancy and lactation?. Adv. Nutr. 5, 779–784 (2014).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Andreas, N. J. et al. Human breast milk: A review on its composition and bioactivity. Early Hum. Dev. 91, 629–635 (2015).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Al-Shehri, S. S. et al. Breastmilk-Saliva Interactions Boost Innate Immunity by Regulating the Oral Microbiome in Early Infancy. PLoS One 10, e0135047 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kageyama, S. et al. High-level acquisition of maternal oral bacteria in formula-fed infant oral microbiota. mBio 13, e03452–21 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Galazzo, G. et al. Development of the microbiota and associations with birth mode, diet, and atopic disorders in a longitudinal analysis of stool samples, collected from infancy through early childhood. Gastroenterology 158, 1584–1596 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Kononen, E. Development of oral bacterial flora in young children. Ann. Med. 32, 107–112 (2000).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Pessoa, L. & Galvão, V. Clinical aspects of congenital syphilis with Hutchinson’s triad. BMJ Case Rep. 2011, bcr1120115130 (2011).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Jedeon, K. et al. Estrogen and bisphenol A affect male rat enamel formation and promote ameloblast proliferation. Endocrinology 155, 3365–3375 (2014).

    Article 
    PubMed 

    Google Scholar 

  • Saadaoui, M. et al. Oral microbiome and pregnancy: A bidirectional relationship. J. Reprod. Immunol. 145, 103293 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • de Jonge, L. et al. Antibiotics prescribed before, during and after pregnancy in the Netherlands: a drug utilization study. Pharmacoepidemiol. Drug Saf. 23, 60–68 (2014).

    Article 
    PubMed 

    Google Scholar 

  • Wormser, G. P. et al. How safe is doxycycline for young children or for pregnant or breastfeeding women?. Diagn. Microbiol. Infect. Dis. 93, 238–242 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Abadie, R. B. et al. Review of Teratogenic Effects of Leflunomide, Accutane, Thalidomide, Warfarin, Tetracycline, and Angiotensin-Converting Enzyme Inhibitors. Cureus 15, e50465 (2023).

    PubMed 
    PubMed Central 

    Google Scholar 

  • Jacobsen, P. E. et al. Developmental enamel defects in children prenatally exposed to anti-epileptic drugs. PLoS One 8, e58213 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Leite, G. A. et al. Exposure to lead exacerbates dental fluorosis. Arch. Oral. Biol. 56, 695–702 (2011).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Salmela, E. et al. Combined effect of fluoride and 2,3,7,8-tetrachlorodibenzo-p- dioxin on mouse dental hard tissue formation in vitro. Arch. Toxicol. 85, 953–963 (2011).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Sahlberg, C. et al. Combined effect of amoxicillin and sodium fluoride on the structure of developing mouse enamel in vitro. Arch. Oral. Biol. 58, 1155–1164 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Morkmued, S. et al. Retinoic acid excess impairs amelogenesis inducing enamel defects. Front. Physiol. 7, 673 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Henning, P. et al. Retinoid receptors in bone and their role in bone remodeling. Front. Endocrinol. 6, 31 (2015).

    Article 

    Google Scholar 

  • Till, C. et al. Health risks and benefits of fluoride exposure during pregnancy and infancy. Annu. Rev. Public Health 46, 253–274 (2025).

    Article 
    PubMed 

    Google Scholar 

  • Varayoud, J. et al. Long-lasting effects of neonatal bisphenol A exposure on the implantation process. Vitam. Horm. 94, 253–275 (2014).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Perng, W. et al. Early life exposure in Mexico to environmental toxicants (ELEMENT) project. BMJ Open 9, e030427 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Suwannakul, B. et al. Organophosphate pesticide exposures in early and late pregnancy influence different aspects of infant developmental performance. Toxics 9, 99 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gunier, R. B. et al. Determinants of manganese in prenatal dentin of shed teeth from CHAMACOS children living in an agricultural community. Environ. Sci. Technol. 47, 11249–11257 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Arora, M. et al. Determining fetal manganese exposure from mantle dentine of deciduous teeth. Environ. Sci. Technol. 46, 5118–5125 (2012).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wu, H. et al. A metabolomic study on the association of exposure to heavy metals in the first trimester with primary tooth eruption. Sci. Total Environ. 723, 138107 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Rohilla, M. Etiology of various dental developmental anomalies: Review of literature. J. Dent. Probl. Solut. 4, 19–25 (2017).

    Article 

    Google Scholar 

  • McKinney, et al. Developmental disturbances of the teeth, anomalies of shape and size. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing (2025).

  • Niederman, R. Pregnancy gingivitis and causal inference. Evid. Based Dent. 14, 107–108 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Macpherson, A. J. & Uhr, T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 303, 1662–1665 (2004).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Jeurink, P. V. et al. Human milk: a source of more life than we imagine. Benef. Microbes 4, 17–30 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Madianos, P. N. et al. Adverse pregnancy outcomes (APOs) and periodontal disease: pathogenic mechanisms. J. Periodontol. 84, S170–S180 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Xu, B. & Han, Y. W. Oral bacteria, oral health, and adverse pregnancy outcomes. Periodontol 2000 89, 181–189 (2022).

    Article 
    PubMed 

    Google Scholar 

  • González-Jaranay, M. et al. Periodontal status during pregnancy and postpartum. PLoS One 12, e0178234 (2017).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Hashim, R. Self-reported oral health, oral hygiene habits and dental service utilization among pregnant women in United Arab Emirates. Int. J. Dent. Hyg. 10, 142–146 (2012).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Ibhawoh, L. & Enabulele, J. Endodontic treatment of the pregnant patient: Knowledge, attitude and practices of dental residents. Niger. Med. J. 56, 311–316 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Koyuncuoglu, C. Z. et al. Rational use of medicine in dentistry: do dentists prescribe antibiotics in appropriate indications?. Eur. J. Clin. Pharmacol. 73, 1027–1032 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Aliabadi, T. et al. Antibiotic use in endodontic treatment during pregnancy: A narrative review. Eur. J. Transl. Myol. 32, 10813 (2022).

    PubMed 
    PubMed Central 

    Google Scholar 

  • Tripathi, R. Incidence of pericoronitis and impacted 3rd molar in pregnant patients visiting dental OPD. Int. J. Adv. Res. 4, 1737–1741 (2016).

    Article 

    Google Scholar 

  • McArdle, L. W. et al. Diseases associated with mandibular third molar teeth. Br. Dent. J. 224, 434–440 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Albalbisi, A. et al. Review etiology, evaluation, and treatment of pericoronitis. J. Healthc. Sci. 2, 457–462 (2022).

    Google Scholar 

  • American Dental Association. Oral health topics: pregnancy (2019). Available at: https://www.ada.org/en/member-center/oral-health-topics/pregnancy.

  • Committee Opinion No. 569 Oral health care during pregnancy and through the lifespan. Obstet. Gynecol. 122, 417–422 (2013).

    Article 

    Google Scholar 

  • European Federation of Periodontology. The Relationship between Oral Health and Pregnancy: Recommendations for women (2020). Available at: https://www.efp.org/fileadmin/uploads/efp/Documents/Campaigns/Oral_Health_and_Pregnancy/Guidelines/guidelines-women.pdf

  • Horowitz, A. M. et al. Obstetric Providers’ Role in Prenatal Oral Health Counseling and Referral. Am. J. Health Behav. 43, 1162–1170 (2019).

    Article 
    PubMed 

    Google Scholar 

  • Sant’Ana, A. C. et al. Periodontal treatment during pregnancy decreases the rate of adverse pregnancy outcome: a controlled clinical trial. J. Appl. Oral. Sci. 19, 130–136 (2011).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wasylko, L. et al. A review of common dental treatments during pregnancy: implications for patients and dental personnel. J. Can. Dent. Assoc. 64, 434–439 (1998).

    CAS 
    PubMed 

    Google Scholar 

  • Paglia, L. & Colombo, S. Perinatal oral health: focus on the mother. Eur. J. Paediatr. Dent. 20, 209–213 (2019).

    CAS 
    PubMed 

    Google Scholar 

  • Ather, A. et al. Pharmacotherapy during Pregnancy: An Endodontic Perspective. J. Endod. 46, 1185–1194 (2020).

    Article 
    PubMed 

    Google Scholar 

  • National Council on Radiation Protection and Measurements. Report No. 145: Radiation Protection in Dentistry (NCRP, 2003).

  • European Commission. Radiation Protection No. 136: European Guidelines on Radiation Protection in Dental Radiology (Office for Official Publications of the European Communities, 2004).

  • Canada Dental Association. CDA Position on Control of X-Radiation in Dentistry (2005). Available at: https://www.cda-adc.ca/_files/position_statements/xradiation.pdf

  • White, S. C. & Pharoah, M. J. Oral Radiology: Principles and Interpretation 8th edn (Mosby Elsevier, 2018).

  • National Radiological Protection Board. Guidance Notes for Dental Practitioners on the Safe Use of X-Ray Equipment (Department of Health, 2001).

  • Environmental Health Directorate, Canada. Safety Code 30: Radiation Protection in Dentistry (Minister of Health, 2000)

  • Guo, X. L. et al. [Standards and guidelines of radiation protection and safety in dental X-ray examinations]. Zhonghua Kou Qiang Yi Xue Za Zhi 52, 762–772 (2017).

    CAS 
    PubMed 

    Google Scholar 

  • Gamba, T. O. et al. Impact of dental imaging on pregnant women and recommendations for fetal radiation safety: A systematic review. Imaging Sci. Dent. 54, 1–11 (2024).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Lin, Z. et al. Expert consensus on imaging diagnosis and analysis of early correction of childhood malocclusion. Int. J. Oral. Sci. 17, 21 (2025).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Tanna, N. K. et al. Imaging in orthodontics. Dent. Clin. North Am. 65, 623–641 (2021).

    Article 
    PubMed 

    Google Scholar 

  • Oenning, A. C. et al. Cone-beam CT in paediatric dentistry: DIMITRA project position statement. Pediatr. Radiol. 48, 308–316 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Enabulele, J. & Ibhawoh, L. Resident obstetricians’ awareness of the oral health component in management of nausea and vomiting in pregnancy. BMC Pregnancy Childbirth 14, 388 (2014).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Little, J. W. et al. Dental Management of the Medically Compromised Patient 10th edn (Mosby Elsevier, 2023).

  • Fayans, E. P. et al. Local anesthetic use in the pregnant and postpartum patient. Dent. Clin. North Am. 54, 697–713 (2010).

    Article 
    PubMed 

    Google Scholar 

  • Lin, K. J. et al. Maternal exposure to amoxicillin and the risk of oral clefts. Epidemiology 23, 699–705 (2012).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Puhó, E. H. et al. Drug treatment during pregnancy and isolated orofacial clefts in Hungary. Cleft Palate Craniofac. J. 44, 194–202 (2007).

    Article 
    PubMed 

    Google Scholar 

  • Gottberg, B. et al. Prenatal effects by exposing to amoxicillin on dental enamel in Wistar rats. Med. Oral. Patol. Oral. Cir. Bucal 19, e38–e43 (2014).

    Article 
    PubMed 

    Google Scholar 

  • Kenyon, S. et al. Antibiotics for preterm rupture of membranes. Cochrane Database Syst. Rev. 12, CD001058 (2013).

    Google Scholar 

  • Oberoi, S. S. et al. Antibiotics in dental practice: how justified are we. Int. Dent. J. 65, 4–10 (2015).

    Article 
    PubMed 

    Google Scholar 

  • Sá del Fiol, F. et al. Antibiotics and pregnancy. Pharmazie 60, 483–493 (2005).

    PubMed 

    Google Scholar 

  • Marcos, Z. Arriving too early. Lancet Neurol. 12, 332–333 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Lawn, J. E. et al. Born too soon: accelerating actions for prevention and care of 15 million newborns born too soon. Reprod. Health 10, S6 (2013).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chang, H. H. et al. Preventing preterm births: analysis of trends and potential reductions with interventions in 39 countries with very high human development index. Lancet 381, 223–234 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Soilly, A. L. et al. Economic analysis of the costs associated with prematurity from a literature review. Public Health 128, 43–62 (2014).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Gutierrez Gossweiler, A. & Martinez-Mier, E. A. Chapter 6: Vitamins and Oral Health. Monogr. Oral. Sci. 28, 59–67 (2020).

    Article 
    PubMed 

    Google Scholar 

  • Mortensen, N. B. et al. Vitamin D status and tooth enamel hypomineralization are not associated in 4-y-old children: An Odense Child. Cohort study J. Steroid Biochem. Mol. Biol. 221, 106130 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Rosier, B. T. et al. Resilience of the Oral Microbiota in Health: Mechanisms That Prevent Dysbiosis. J. Dent. Res. 97, 371–380 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Zhou, F. et al. The association between serum 25-hydroxyvitamin D levels and dental caries in US adults. Oral. Dis. 26, 1537–1547 (2020).

    Article 
    PubMed 

    Google Scholar 

  • Mahmood, M. K. et al. Association between vitamin D levels and dental caries: A systematic review and dose-response meta-analysis of cross-sectional studies. Appl. Sci. 13, 9883 (2023).

    Article 
    CAS 

    Google Scholar 

  • Hujoel, P. P. Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis. Nutr. Rev. 71, 88–97 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Nørrisgaard, P. E. et al. Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial. JAMA Pediatr. 173, 924–930 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Dudding, T. et al. Re-Examining the Association between Vitamin D and Childhood Caries. PLoS One 10, e0143769 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Herzog, K. et al. Association of vitamin D and dental caries in children: Findings from the National Health and Nutrition Examination Survey, 2005–2006. J. Am. Dent. Assoc. 147, 413–420 (2016).

    Article 
    PubMed 

    Google Scholar 

  • Anunciação, B. H. et al. Knowledge, attitudes, and practices of prenatal care practitioners regarding oral health in pregnancy—A systematic review. Int. J. Gynaecol. Obstet. 162, 449–461 (2023).

    Article 
    PubMed 

    Google Scholar 

  • Jakovljevic, A. et al. The association between apical periodontitis and adverse pregnancy outcomes: a systematic review. Int. Endod. J. 54, 1527–1537 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Perinatal and Infant Oral Health Care. Pediatr. Dent. 39, 208–212 (2017).

  • Kessler, J. L. A Literature Review on Women’s Oral Health Across the Life Span. Nurs. Women’s. Health 21, 108–121 (2017).

    Article 

    Google Scholar 

  • Wu, M. et al. Relationship between gingival inflammation and pregnancy. Mediators Inflamm. 2015, 623427 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kaan, A. M. & Zaura, E. Oral Microbiome Transmission and Infant Feeding Habits. mBio 13, e0032522 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Brahm, P. & Valdés, V. Beneficios de la lactancia materna y riesgos de no amamantar. Rev. Chil. Pediatr. 88, 7–14 (2017).

    Article 
    PubMed 

    Google Scholar 

  • Peres, K. G. et al. Exclusive Breastfeeding and Risk of Dental Malocclusion. Pediatrics 136, e60–e67 (2015).

    Article 
    PubMed 

    Google Scholar 

  • Borrie, F. Breastfeeding and occlusal development. Evid. Based Dent. 19, 5 (2018).

    Article 
    PubMed 

    Google Scholar 

  • Sum, F. H. et al. Association of breastfeeding and three-dimensional dental arch relationships in primary dentition. BMC Oral. Health 15, 30 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • World Health Organization. Breastfeeding. Available at: https://www.who.int/health-topics/breastfeeding#tab=tab_1

  • Peres, K. G. et al. Effects of breastfeeding and sucking habits on malocclusion in a birth cohort study. Rev. Saude Publica 41, 343–350 (2007).

    Article 
    PubMed 

    Google Scholar 

  • Narbutytė, I. et al. Relationship between breastfeeding, bottle-feeding and development of malocclusion. Stomatologija 15, 67–72 (2013).

    PubMed 

    Google Scholar 

  • Chen, X. et al. Effects of breast-feeding duration, bottle-feeding duration and non-nutritive sucking habits on the occlusal characteristics of primary dentition. BMC Pediatr. 15, 46 (2015).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Pires, S. C. et al. Influence of the duration of breastfeeding on quality of muscle function during mastication in preschoolers: a cohort study. BMC Public Health 12, 934 (2012).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ling, H. T. B. et al. The association between nutritive, non-nutritive sucking habits and primary dental occlusion. BMC Oral. Health 18, 145 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Aarts, C. et al. Breastfeeding patterns in relation to thumb sucking and pacifier use. Pediatrics 104, e50 (1999).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Sexton, S. & Natale, R. Risks and benefits of pacifiers. Am. Fam. Physician 79, 681–685 (2009).

    PubMed 

    Google Scholar 

  • Comina, E. et al. Pacifiers: a microbial reservoir. Nurs. Health Sci. 8, 216–223 (2006).

    Article 
    PubMed 

    Google Scholar 

  • Agarwal, S. S. et al. Association between breastfeeding duration, non-nutritive sucking habits and dental arch dimensions in deciduous dentition: a cross-sectional study. Prog. Orthod. 15, 59 (2014).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • link

    Leave a Reply

    Your email address will not be published. Required fields are marked *

    Copyright © All rights reserved. | Newsphere by AF themes.